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10.1016/j.arr.2015.01.001 18 LiH.LowY

Epub 2013 Sep 17

Because regulatory approval requires: robust human clinical trials demonstrated efficacy established long-term safety These data are currently lacking

References: (1) Graf M, Baumann JB, Girard J, Tobler HJ, Schoenenberger GA

BPC-157 appears to act upstream of VEGF transcription, with documented upregulation of VEGF mRNA and protein expression in both in vitro endothelial cell cultures and in vivo wound models