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The takeaway: switching to nicotine pouches from cigarettes is a positive harm-reduction step but it is not pharmacologically neutral for patients on these medications

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Noble rum from cane plantations under the hot Caribbean sun

Tobacco Suitable for: Key stage 5 Time period: Early modern 1485-1750 Curriculum topics: The British Empire, The Stuarts Suggested inquiry questions: What do these documents reveal about the origins of the English tobacco trade

The researchers found that smokers had lower levels of certain protective immune cells and higher levels of immune cells that cause chronic inflammation

The mechanism by which bupropion enhances the ability of patients to abstain from smoking is unknown