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5a) and 3.5-fold in ATCC18224 strain (Fig

This review discusses the intricate regulatory pathways of mitophagy in PDAC, focusing on the PINK1/Parkin pathway and receptor-mediated pathways

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10.1172/jci.insight.96910 28

A.MacchiB.GrelliS.MoscaC.et al

When mitochondrial membrane potential declines, PINK1 stabilizes on the outer mitochondrial membrane, recruiting and activating the E3 ubiquitin ligase Parkin (Table 1)