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Oral corticosteroids (e.g., prednisone, prednisolone), due to their adverse effects (e.g., muscle weakness and respiratory failure), are not recommended for long-term use in patients with COPD (GOLD 2011)

2012 Feb;51(1):1-18

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(This might relate to propofols inhibition of NMDA receptors, which blocks tolerance and withdrawal.) Propofol suppresses respiration, which can be helpful among ventilated patients to reduce ventilator dyssynchrony