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stiffness and resistance to limb movement caused by increased muscle tone and/or an excessive and continuous contraction of muscles, which may be uniform (lead-pipe rigidity) or ratchety (cogwheel rigidity), and which may be associated with joint pain

The pen does not need to be at room temperature continuously

however, caution is still necessary

Because BPC-157 is studied across vascular and repair models, NO signalling is a major pathway of interest

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Independent published work typically used BPC-157 or T4 alone, in animal models or in clinical trials with full-length T4 (RGN-259/RGN-352)