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Host-directed therapy, an untapped opportunity for antimalarial intervention

on the immune system) or negative effects (e.g

however, its use did not lead to a significant improvement in motor recovery (Ruzicka et al., 2019)

Histopathology revealed that exposure to DEHP and MEHP substantially increased the infiltration of inflammatory cells into the lungs, as compared to exposure to vehicle controls ( Figure 1E )

[DOI] [PMC free article] [PubMed] [Google Scholar] 311.Morris GP, Clark IA and Vissel B, Acta Neuropathol, 2018, 136, 663689

It is critical to understand these pathways as we attempt to understand disease susceptibility in target populations