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The challenge and prospect of mRNA therapeutics landscape

This likely reflects individual differences in the extent of thermogenic activation

An exuberant innate immunoinflammatory response is a hallmark of severe COVID-19 with the cytokine storm, hyperinflammation, and multiorgan failure, which are correlated with elevated blood levels of proinflammatory cytokines and chemokines, e.g., IL-1, IL-2, IL-4, IL-6, IL-8, IL-10, IL-17, IFN-, and TNF- (9)

Svellec, F., Fedorov, A

In one embodiment, the synthetic nanocarriers are formulated to release the therapeutic agent at a specified pH and/or after a desired time interval

[DOI] [PMC free article] [PubMed] [Google Scholar] 108.Performance evaluation of smart glove applied to experimental rig to control human hand tremor for Parkinson disease