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Mitsubishi Tanabe Pharma America presents final results from the global, phase 3b MT-1186-A02 post-marketing study of radicava (edaravone) in ALS

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To examine if ammonia-induced increases in extracellular glutamate were mediated by excitatory amino-acid transporters, the reverse dialysis of ammonia, the glutamate transporter inhibitor, DL- threo - -benzyloxyaspartic acid (TBOA), or the combination of the two directly into the striatum of awake, freely moving rats was conducted

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The core molecular mechanism of ferroptosis includes the regulation of oxidation and the balance between damage and antioxidant defense