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A higher nationwide smoking age would save lives A 2015 report from the Institute of Medicine (IOM) found raising the smoking age to 21 could prevent approximately 223,000 premature deaths among Americans born between 2000 and 2019

J Pain Symptom Manage 58(4):605-613, 2019

Management challenges at end-of-life in a patient with agitated delirium and benzodiazepine withdrawal at comprehensive cancer care center

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Some people have reported developing mouth lesions from using them too much

Neurogastroenterol Motil 32:e13789 Yang Y, Yang C, Lei Z, Rong H, Yu S, Wu H, Guo J (2021) Cigarette smoking exposure breaks the homeostasis of cholesterol and bile acid metabolism and induces gut microbiota dysbiosis in mice with different diets