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Pediatr., 47, 132137

doi: 10.1111/jcmm.18044 77 De MicheleRCarimiFFrommerWB

100 L of supernatant was mixed with 100 L methanol, centrifuged (42,500 g , 15 min), and filtered through a 0.22-m membrane filter prior to GC analysis

Mormino EC, Betensky RA, Hedden T, Schultz AP, Amariglio RE, Rentz DM, et al

suggested that Sanguinarine aggregated excessive ROS by promoting the activation of NOX3 and consequential inactivation of MsrA and Cys peroxidation of EGFR T790M in EGFR-modulated TKI-resistant cells, which ultimately led to EGFR degradation and cell death 284 (Table 1, Fig