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These findings led to Phase I and II clinical trials of T4 eyedrops (RGN-259) for dry eye and neurotrophic keratopathy, making the ocular surface one of the most clinically advanced use areas for the broader T4/TB-500 compound class

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[DOI] [PMC free article] [PubMed] [Google Scholar] 488.Xiang W, Li L, Zhao Q, Zeng Y, Shi J, Chen Z, et al

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This includes managing stress, maintaining balanced hormones, eating a nutrient-rich diet, improving sleep quality, and avoiding harsh heat or chemical treatments