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Pink1 and Parkin KO mice both showed an increase in increased inflammation, but antioxidants abolished CASP1 activation, suggesting a role for ROS in the inflammation associated with impaired mitophagy (Sliter et al., 2018)

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The Importance of Consistent, Moderate Dosing When it comes to glutathione, the goal is to maintain a steady level of the antioxidant in your system rather than attempting to "shock" your body with high doses

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