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Indeed, most of the JmjC histone demethylases identified so far are capable of efficiently catalyzing demethylation of trimethylated lysines, and in most cases, they preferentially bind the trimethylated substrates [61, 62]

Dies wirft die Frage auf, ob eine mitochondriale Dysfunktion ein Faktor sein knnte, der zum Fortschreiten dieser Erkrankung fhrt

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Furthermore, stimulation has recently been shown to be associated with increased neurogenesis in the perilesional cortex, as well as in the mediodorsal and ventrolateral thalamic relay nuclei, providing another mechanism through which the facilitative effects of stimulation may occur