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Abnormal hemostatic parameters (prolonged aPTT and PT) are indicative of severe hepatic dysfunction or DIC

doi: 10.1186/s12916-022-02478-y 8 SuYGaoJKaurPWangZ

Regulation of gene expression once bound to the VDRs, calcitriol regulates the expression of genes involved in calcium & phosphorus absorption in the intestines, bone health, immune function, and cell growth

Evaluations of VAS and FIQ-R were collected at baseline, after 1, 2 and 3 months from the start of treatment, and subsequently every 3 months throughout the 15-month maintenance therapy