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Prentki M, Matschinsky FM and Madiraju SR

[Abstract]2025 May 8:2025.05.08.652791

Importantly, PDT may well initiate ICD

PD-L1 is a novel direct target of HIF-1, and its blockade under hypoxia enhanced MDSC-mediated T-cell activation

In contrast, in 3xTg males, CR-fed mice had upregulation of both pro-inflammatory ( Il1b and Il6 ) and anti-inflammatory ( Il10 ) genes compared to AL- and DL-fed groups (Fig