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Cysteine is the rate-limiting substrate
BMC Public Health 23, 859
Chronic Inflammation and Oxidative Stress Chronic inflammation and oxidative stress are intertwinedoxidative stress triggers inflammatory responses and inflammation, further generating reactive oxygen species
We suggest that the efficiency of thiol oxidation catalyzed by SOD1 is a function of its Cu 2+ content, which in turn reflected the efficiency, with which Cu 2+ was incorporation into the tested SOD1 variants upon the reconstitution (see Methods)
In addition, our data confirm that IGF-1R regulates myofascial pain mainly through the PI3K/AKT pathway
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