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Notably, one participant with a history of B12-responsive acne developed lesions following B12 administration during the study

When conducting research with AOD 9604, it is necessary to strictly abide by the relevant safety regulations and operating procedures to ensure the safety of the laboratory personnel

Rescue medication was available for patients whose fasting plasma glucose exceeded the predefined limits of 15.0 mmol/L from week 8, 13.3 mmol/L from week 9 to week 20, and 11.1 mmol/L from week 21 to week 32

rodentium growth or virulence at physiological relevant cobalamin levels

Development and Selectivity The development of AOD9604 was based on the observation that the C-terminal region of growth hormone possesses independent metabolic regulatory functions distinct from the growth-promoting effects mediated by the N-terminal receptor-binding domain

Second: the short plasma half-life (~30 min) was insufficient, by the time the fragment circulating in the blood was supposed to act, it had already been metabolized