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Description

On the inflammatory front, curcumin inhibits microglial activation and downregulates the expression of inflammatory enzymes and cytokinesfor instance, it suppresses iNOS and COX-2 induction and lowers levels of TNF- and other interleukins in activated glial cells (72)

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If persistent, dose adjustment usually addresses it

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Rotenone-induced impairment of mitochondrial electron transport chain confers a selective priming signal for NLRP3 inflammasome activation

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Intervening in inflammatory signaling pathways is also a key strategy

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