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Bousquet et al., 2020

Alzheimers disease Alzheimers disease (AD) is a multifactorial disease characterized by the degeneration of the cells in the brain (Knopman et al

Plays a role in energy production, DNA repair, circadian rhythm, metabolism, muscle function, tissue repair and mental clarity

BMJ (2006) 333:575

For inducing the TCA cycle to produce more energy, G2 increased PDH activity that enhanced CA content, which further increased isocitrate dehydrogenase (ICDH) activity and provided intermediate products for the G

Recent evidence has shown that astrocytes are arranged in non-overlapping domains forming a syncytial network that may contact approximately 160.000 synapses, thus integrating neural activity with the vascular network [4,28]