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In an exploratory analysis of the results of the REWIND trial, a CVOT for dulaglutide (another once-weekly GLP-1RA), a highly significant reduction of 13%-14% was observed in the risk of substantive cognitive impairment, also after adjustment for baseline scores, age ,sex, ethnic origin or education [26]

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Subgroup analyses were conducted to identify potential sources of this variation, revealing that factors such as animal species, treatment strategies, modeling approaches, and dosages may account for these differences

87 However, cancer cells maintain high amounts of NAD + mainly by upregulation of the NAMPT enzyme

Indian journal of community medicine: official publication of Indian Association of Preventive & Social Medicine

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