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These molecules are highly soluble in water, so their transport to various tissues does not require the involvement of lipoproteins (104, 105)

Also, it poses an adverse effect on patients with high cholesterol levels, by increasing low-density lipoprotein cholesterol (LDL-C) and TGs and decreasing HDL-C 9

On that, the FDA is undecided and has been for some time

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More long-term research is needed to confirm if it has ill effects on the heart