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BTZ (1 mg/kg) and Betaine (500 mg/kg) were injected intraperitoneal three times every week

This reaction not only limits peroxynitrite (ONOO ) formation and preserves nitric oxide (NO) bioavailability but also supports compartmentalized redox signaling critical for vascular tone, angiogenesis, and neuronal function

Measurement of ROS Production ARPE-19 Cells (5,000/well) were seeded in white opaque 96-well plates (Corning, Sigma-Aldrich) and incubated overnight

The tocopherol transfer protein mediates vitamin E trafficking between cerebellar astrocytes and neurons

The sequence order is important