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US20140134222A1 - Topical benfotiamine and pyridoxamine compositions - Google Patents Topical benfotiamine and pyridoxamine compositions Download PDF Info Publication number US20140134222A1 US20140134222A1 US14/158,124 US201414158124A US2014134222A1 US 20140134222 A1 US20140134222 A1 US 20140134222A1 US 201414158124 A US201414158124 A US 201414158124A US 2014134222 A1 US2014134222 A1 US 2014134222A1 Authority US United States Prior art keywords composition skin acid pyridoxamine benfotiamine Prior art date Legal status (The legal status is an assumption and is not a legal conclusion

Whether used in vitro or in animal models, high-purity peptides are essential for generating reproducible, publication-quality data

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Inhibitors are needed for therapy, but development of potent, specific inhibitors of GGT1 has been hampered by a lack of structural information regarding substrate binding and cleavage

Angew Chem Int Ed Engl 45:75537557

Rovira-Llopis S, Banuls C, Diaz-Morales N, Hernandez-Mijares A, Rocha M, Victor VM