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A mutation in this gene can reduce the enzyme's efficiency,potentially leading to various health issues such as: Elevated homocysteine levels (increasing the risk of cardiovascular disease) Chronic fatigue Migraines Hormonal imbalances Depression and anxiety Poor detoxification Pregnancy complications Since the MTHFR mutation can affect how your body process esessential nutrients, those with this mutation may need to take specific steps to optimize their health and minimize potential risks

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Pollard et al., 2010

These protective effects support both acute cognitive enhancement and long-term brain health maintenance

Oxaloacetate has also been investigated for therapeutic potential in conditions characterized by chemical liver injury

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