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Individuals with XPA pathogenic variants in the DNA binding region (amino acids 98219) may have a more severe presentation that includes neurological findings.[68] Individuals within the XPC complementation group have higher incidences of ocular damage.[67] A very small number of people in the XPB, XPD, and XPG complementation groups have been identified as having xeroderma pigmentosum-Cockayne syndrome (XP-CS) complex

Losartan can improve disease manifestations in the lungs, an event that cannot plausibly relate to improved hemodynamics C1039G/+ [4]

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The unfolded protein response and cell fate control

Trials have been relatively small, and a gold standard (randomized, placebo-controlled) study has not yet been done

doi: 10.1007/s12272-021-01352-4 111 SuLZhangJGomezHKellumJAPengZ