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The breadth of documented activity reflects what the original investigators have described as systems-level pharmacology: rather than acting through a single high-affinity receptor, BPC-157 appears to modulate multiple intersecting cellular pathways including nitric oxide signalling, growth-factor receptor expression, dopamine and serotonin metabolism, and angiogenic vessel formation

doi: 10.1111/j.1460-9568.2011.07626.x

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Once transplanted, functional immune-regulating cells could act as drug reservoirs and produce cytokines and growth factors to assist co-transplanted insulin-producing cells on demand

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