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2018 Jan 5;122(1):5873

PubMed Central PMCID: PMC7564022 Sex Hormone Signaling Suppresses Ferroptosis via Phospholipid Remodeling (2023) Cancer Discov 13(8):1759

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AAV are not without limitations, which include small packaging capacity (5 kilobases), limiting delivery of large genes, and development of antibodies (while AAV is poorly immunogenic, both the capsid and transgene can elicit an immune response)