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Interestingly, we found that increased VGF expression was accompanied by increased glucagon secretion (Supplementary Fig

In addition to the adverse reactions observed for CAVERJECT, the following adverse reactions have been reported in clinical studies of CAVERJECT IMPULSE: CAVERJECT IMPULSE was evaluated in 87 patients in an open-label crossover study of 6 weeks treatment duration that compared the formulation of alprostadil for injection contained in CAVERJECT IMPULSE with the formulation contained in CAVERJECT

Avoid freezing the mixed solution, since freezethaw can degrade the peptide

Keep in mind that evidence is preliminary and largely based on animal studies or small human trials

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