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Lee S, Devanney NA, Golden LR et al (2023) APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge

I passed on the 2nd dose as well

[Google Scholar] [PubMed] [CrossRef] 155

The descendant enzymes of the original ATP-binding cassettes (ABC) present in extant (and presumably ancient extinct) zooxantellae, act as ATP-dependent efflux transporters in pumping out molecular chemotherapeuticals from malignantly transformed (cancer) cells in multicellular vertebrate mammalian (human) hosts (as referenced in 7)