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In addition to evidence of efficacy, the group also considered safety

The mice were housed in standard laboratory cages, with a maximum of 5 animals per cage, under SPF conditions, with regulation of temperature (22C 1C) and humidity (55%) and a 12-h:12-h dark-light cycle, and were free to get food and water

Studies highlight the advantages of CoQ10 [38]

This article summarizes the mechanisms, diagnostic approaches, and therapeutic strategies for ferroptosis in CNS injuries

184, 185, 186, 187, 188 In spite of an acceptable safety profile and promising antineoplastic activity, the clinical development of all these agents appears to stand at an impasse, at least as judged by the low rate of ongoing versus completed, terminated or withdrawn trials (source www.clinicaltrials.gov)

However, in other epidemiological studies in prostate cancer patients these associations were not confirmed (75, 76)